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Tafazine Plus extended-release tablet 10/1000mg

This drug is administered as an adjunct to diet and exercise therapy to improve glycemic control in adult patients with type 2 diabetes who are suitable for combined administration of dapagliflozin and metformin.

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The dosage of this drug should be individualized based on the patient's current treatment, efficacy and tolerability, without exceeding the maximum recommended dose of 10 mg of dapagliflozin and 2000 mg of sustained-release metformin. This medication is generally administered once daily with dinner. The maximum dose of this drug is 10 mg of dapagliflozin/2,000 mg of extended-release metformin once a day, and is administered as 2 tablets of 5 mg/1,000 mg.

If you have never received diabetes medication before and have difficulty controlling blood sugar levels sufficiently with monotherapy: When used as initial therapy in those who have not previously received diabetes medication, the recommended starting dose of this drug is one tablet of 5 mg/500 mg or 10 mg/500 mg once daily. Adjust the dose gradually to reduce the gastrointestinal side effects of metformin. In patients switching from dapagliflozin and metformin combination therapy to this drug, the dose of this drug can be started at the existing dose of dapagliflozin and metformin. When switching from metformin immediate-release to sustained-release formulations, glycemic control should be closely monitored and dosage adjustments should be made appropriately.

The safety and effectiveness of this drug have not been specifically evaluated in patients switching to this drug from other hypoglycemic agents. Any changes in the treatment of patients with type 2 diabetes should be made under careful monitoring because they may cause changes in glycemic control. This medication should be swallowed whole and should never be crushed, cut, or chewed. Occasionally, the inactive ingredients of this medicine may be excreted in the feces in the form of soft tablet-like hydrates. renal impairment